Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301179 | 1.00 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10779221 | 0.83 | CSNK2A1 (0.49) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL15931768 | 0.83 | FFAR4 (0.41) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL24915820 | 0.83 | KDM4E (0.41) | RAB9AKDM4EPOLBMAPTAPAF1 | |
| SCHEMBL7820279 | 0.83 | TAAR1 (0.49) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5288482 | 0.81 | USP2 (0.50) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL15345630 | 0.81 | USP2 (0.50) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL24899349 | 0.80 | SLC13A5 (0.49) | KDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL11216680 | 0.80 | NPC1 (0.40) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL15808851 | 0.79 | KMT2A (0.42) | KMT2ANPC1RAB9AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |