SCHEMBL11216680

SCHEMBL11216680

Cc1ccc(C)c(CC(=O)CC(C)C(=O)O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 2/20 0.38
SLC22A12 Q96S37 1/20 0.38
SRC P12931 2/20 0.38
BRD4 O60885 1/20 0.38
STING1 Q86WV6 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 2/20 0.36
KDM4C Q9H3R0 2/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.35
KDM4A O75164 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301179 0.80 MEN1 (0.45) NPC1RAB9ATAAR1ALDH1A1CYP2C19
SCHEMBL24899418 0.80 MEN1 (0.45) NPC1RAB9ATAAR1ALDH1A1CYP2C19
SCHEMBL11214983 0.78 MEN1 (0.41) NPC1RAB9ATAAR1ALDH1A1CYP2C19
SCHEMBL7820279 0.78 TAAR1 (0.49) NPC1RAB9ATAAR1ALDH1A1CYP2C19
SCHEMBL27959986 0.76 TAAR1 (0.46) NPC1RAB9ATAAR1SLC22A12SRC
SCHEMBL29375293 0.76 SRC (0.58) NPC1RAB9ATAAR1ALDH1A1SLC22A12
SCHEMBL37138 0.76 SRC (0.58) NPC1RAB9ATAAR1ALDH1A1SLC22A12
SCHEMBL3015869 0.75 HTT (0.45) NPC1RAB9ATAAR1ALDH1A1SLC22A12
Hydrochloric Acid SCHEMBL2531969 0.74 SRC (0.56) NPC1RAB9ATAAR1ALDH1A1SLC22A12
SCHEMBL28007584 0.74 SRC (0.56) NPC1RAB9ATAAR1ALDH1A1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338122-A MITICIDES, HERBICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4283348-A SODIUM ETHOXIDE PROMOTED CYCLIZATION OF LEVULINIC ACID ESTERS UNION CARBIDE CORPORATION (US) 1981-08-11 US disclosed