Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16310461 | 0.86 | HPGD (0.50) | HPGDALDH1A1MAPTMMP9MMP8 | |
| SCHEMBL7064891 | 0.85 | EPHX1 (0.50) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL17992751 | 0.84 | EPHX1 (0.49) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL18369508 | 0.82 | ALDH1A1 (0.47) | HPGDEPHX1ALDH1A1MAPTLTA4H | |
| SCHEMBL20791653 | 0.82 | ALDH1A1 (0.58) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL3901603 | 0.82 | ALDH1A1 (0.58) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL1432589 | 0.82 | ALDH1A1 (0.58) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL18376012 | 0.81 | CPA1 (0.42) | HPGDEPHX1ALDH1A1MAPTLTA4H | |
| SCHEMBL4463351 | 0.81 | EPHX1 (0.49) | HPGDEPHX1ALDH1A1MAPTNPC1 | |
| SCHEMBL18369535 | 0.80 | CPA1 (0.41) | HPGDEPHX1ALDH1A1MAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |