Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644988 | 0.84 | PNMT (0.43) | PNMTEPHX2TPSAB1TPSD1TPSG1 | |
| SCHEMBL29430517 | 0.84 | PNMT (0.47) | EPHX1PNMTKMT2A | |
| SCHEMBL3459355 | 0.84 | PNMT (0.47) | EPHX1PNMTKMT2A | |
| Water SCHEMBL15362024 | 0.83 | PNMT (0.46) | EPHX1PNMTKMT2A | |
| SCHEMBL6502789 | 0.81 | PNMT (0.54) | EPHX1PNMTEPHX2SRD5A2KMT2A | |
| SCHEMBL29541016 | 0.81 | HTT (0.47) | EPHX1PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL6030527 | 0.81 | HTT (0.47) | EPHX1PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL6374771 | 0.80 | PNMT (0.48) | EPHX1PNMTEPHX2KMT2A | |
| Glycine SCHEMBL25183413 | 0.80 | PNMT (0.49) | EPHX1PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL30898587 | 0.80 | PNMT (0.43) | EPHX1PNMTTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560690-B1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2017-03-08 | — | — | EP | disclosed |
| US-9266924-B2 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2560690-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131735-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2011-10-27 | — | — | WO | disclosed |
| EP-2380596-A1 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2011-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | ANXA4, XPNPEP1, ANXA1 | EPHX1 3867/4885HDAC1 861/4885HDAC2 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.