Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24899738 | 0.84 | ALOX5AP (0.36) | FYNALOX5APFEN1PIK3CDABL1 | |
| SCHEMBL24497661 | 0.79 | TYK2 (0.37) | FYNPIK3CABMPR1ATGFBR1ACVRL1 | |
| SCHEMBL29686380 | 0.78 | FYN (0.43) | FYNALOX5APFEN1BMPR1ATGFBR1 | |
| SCHEMBL26983724 | 0.78 | ALOX5AP (0.38) | FYNALOX5APFEN1BMPR1ATGFBR1 | |
| SCHEMBL24498523 | 0.78 | FYN (0.35) | FYNEPHB4BMPR1ATGFBR1ACVRL1 | |
| SCHEMBL23980135 | 0.78 | FYN (0.43) | FYNALOX5APFEN1BMPR1ATGFBR1 | |
| SCHEMBL23980714 | 0.77 | CLK4 (0.41) | FYNKDM4ELMNAMGAMGAA | |
| SCHEMBL24899878 | 0.76 | FYN (0.37) | FYNALOX5APFEN1BMPR1ATGFBR1 | |
| SCHEMBL30780429 | 0.73 | FYN (0.34) | FYNKDRBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL26983728 | 0.73 | FYN (0.34) | FYNKDRBMPR1ATGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |