Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 8/20 | 0.36 |
| ▸ | FEN1 | P39748 | 8/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24899672 | 0.84 | FYN (0.32) | ALOX5APFEN1PIK3CDABL1EGFR | |
| SCHEMBL24899814 | 0.77 | L3MBTL1 (0.38) | CD274PDCD1LG2 | |
| SCHEMBL29740023 | 0.76 | KDM1A (0.43) | ALOX5APFEN1KDM1ACD274PDCD1 | |
| SCHEMBL23925790 | 0.76 | KDM1A (0.43) | ALOX5APFEN1KDM1ACD274PDCD1 | |
| SCHEMBL29686208 | 0.74 | FEN1 (0.44) | ALOX5APFEN1CD274PDCD1 | |
| SCHEMBL24498032 | 0.74 | FEN1 (0.44) | ALOX5APFEN1CD274PDCD1 | |
| SCHEMBL24899878 | 0.74 | FYN (0.37) | ALOX5APFEN1FYN | |
| SCHEMBL24899855 | 0.72 | FYN (0.44) | ALOX5APFEN1FYN | |
| SCHEMBL24498490 | 0.72 | ALOX5AP (0.43) | ALOX5APFEN1FYN | |
| SCHEMBL27295955 | 0.71 | SMN1; SMN2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |