SCHEMBL2490

SCHEMBL2490

C1=Cc2ccccc2C=[N+]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451708 0.71
SCHEMBL451268 0.71
SCHEMBL2841622 0.71 ACHE (0.31)
SCHEMBL3767165 0.69 MAPT (0.53) GAAMAPT
SCHEMBL29398195 0.69
SCHEMBL33554 0.69
SCHEMBL29375766 0.69 MAPT (0.53) GAAMAPT
SCHEMBL29418986 0.69 MAPT (0.53) GAAMAPT
Water SCHEMBL9798116 0.66 MAPT (0.50) GAAMAPT
SCHEMBL8984812 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023165591-A1 COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) 2023-09-07 WO claimed
WO-2023131690-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS MERCK PATENT GMBH (DE) 2023-07-13 WO claimed
CN-110248932-B Pyrimidine tricycloalkenone derivatives for ROR γ inhibition and other uses 里亚塔医药公司 2023-03-10 CN claimed
CN-110248932-A Pyrimidine tricycloalkenone derivatives for ROR γ inhibition and other uses 里亚塔医药公司 2019-09-17 CN claimed
EP-3428202-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2019-01-16 EP claimed
US-9611348-B2 Process of producing polyolefins using metallocene polymerization catalysts and copolymers therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-04-04 US claimed
CN-106456629-A Vmat2 inhibitors for the treatment of hyperkinetic movement disorders 纽罗克里生物科学有限公司 2017-02-22 CN claimed
CN-106061506-A Pharmaceutical compositions comprising an antipsychotic agent and a VMAT2 inhibitor and uses thereof 纽罗克里生物科学有限公司 2016-10-26 CN claimed
CN-105968076-A Spiral organic electroluminescent material and application thereof 中节能万润股份有限公司 2016-09-28 CN claimed
US-9353131-B2 Methods for forming protected organoboronic acids THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-05-31 US claimed
US-5691382-A ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-11-25 US claimed
US-5559140-A VIRICIDES MERRELL PHARMACEUTICALS INC. (US) 1996-09-24 US claimed
EP-0565631-B1 ANTI-VIRAL COMPOUNDS MERRELL PHARMA INC (US) 1996-09-18 EP claimed
CN-1126988-A Difluoro statone analogs MERRELL DOW PHARMA (US) 1996-07-17 CN claimed
EP-0707564-A1 DIFLUORO STATONE ANALOGS MERRELL PHARMACEUTICALS INC. (US) 1996-04-24 EP claimed
WO-1995001958-A1 DIFLUORO STATONE ANALOGS MERRELL PHARMACEUTICALS INC. (US) 1995-01-19 WO claimed
EP-0444506-B1 Silver halide photographic materials containing arylhydrazides DU PONT DEUTSCHLAND (DE) 1994-10-26 EP claimed
EP-0565631-A1 ANTI-VIRAL COMPOUNDS. MERRELL DOW PHARMA (US) 1993-10-20 EP claimed
WO-1992012123-A1 ANTI-VIRAL COMPOUNDS MERRELL DOW PHARMACEUTICALS INC. (US) 1992-07-23 WO claimed
US-5028601-A Substituted with an amino thiazole group and a dihydroxy-pyridone group MEIJI SAIKA KAISHA, LTD. (JP) 1991-07-02 US claimed