Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897084 | 0.82 | EPHX2 (0.50) | FBP1EPHX2SMN1; SMN2RAB9ATSHR | |
| SCHEMBL23519391 | 0.79 | EPHX2 (0.52) | FBP1EPHX2TSHRPPARAABCB11 | |
| SCHEMBL2348011 | 0.77 | EPHX2 (0.51) | FBP1EPHX2SMN1; SMN2TSHRPPARA | |
| SCHEMBL31371124 | 0.76 | EPHX2 (0.43) | FBP1EPHX2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23519249 | 0.76 | EPHX2 (0.50) | FBP1EPHX2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15546762 | 0.75 | POLB (0.49) | FBP1EPHX2SMN1; SMN2TSHRPPARA | |
| SCHEMBL24497220 | 0.75 | POLB (0.50) | EPHX2RAB9ANPC1TSHRPPARA | |
| Hydrochloric Acid SCHEMBL6981964 | 0.75 | EPHX2 (0.49) | FBP1EPHX2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5384911 | 0.75 | TSHR (0.51) | FBP1EPHX2SMN1; SMN2TSHRPPARA | |
| SCHEMBL1221631 | 0.74 | GPR3 (0.45) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |