Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853732 | 0.91 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL9328197 | 0.90 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL9326818 | 0.90 | ADORA2A (0.83) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL23928202 | 0.89 | ADORA2A (0.85) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL9328652 | 0.88 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL30153479 | 0.87 | ADORA2A (0.64) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL23828893 | 0.86 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL29853807 | 0.85 | ADORA2A (0.73) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL23581271 | 0.85 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL29837353 | 0.85 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027075-A1 | SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027075-A1 | SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS | ADORA2A, ADORA2B, ENTPD5 | ADORA2A 1/4885ADORA3 5/4885ADORA1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.