SCHEMBL2490445

SCHEMBL2490445

C[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.57
TAAR1 Q96RJ0 3/20 0.53
SLC6A2 P23975 1/20 0.53
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
HDAC8 Q9BY41 2/20 0.44
LNPEP Q9UIQ6 2/20 0.42
ERAP2 Q6P179 1/20 0.42
DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680265 0.92 SLC7A5 (0.67) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL4453960 0.92 SLC7A5 (0.67) SLC7A5TAAR1SLC6A2ESR1ESR2
Tyrosine SCHEMBL2284684 0.90 SLC7A5 (0.63) SLC7A5TAAR1SLC6A2HDAC8
SCHEMBL16443320 0.89 SLC7A5 (0.56) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL16443319 0.89 SLC7A5 (0.56) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL1684966 0.88 SLC7A5 (0.54) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL1537215 0.88 SLC7A5 (0.54) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL302979 0.88 SLC7A5 (0.54) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL321221 0.87 SLC7A5 (0.61) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL4279625 0.87 SLC7A5 (0.61) SLC7A5TAAR1SLC6A2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478777-A Staphylococcus aureus FnBPA A albumen mimic epitope peptide, mimic epitope peptide combinations and its application with immune protective 安徽农业大学 2017-03-08 CN claimed
CN-115639360-A Preparation of precursor gastrin (PG 80) antibody and establishment of CLIA detection PG80 kit 武汉市朗典精医生物科技有限公司 2023-01-24 CN disclosed
US-20220162656-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2022-05-26 US disclosed
CN-114371280-A Plasma biomarker for broiler AFB1 poisoning diagnosis and application thereof 河南农业大学 2022-04-19 CN disclosed
US-9714898-B2 Structure assessment of heterogeneous polypeptide mixture MOMENTA PHARMACEUTICALS, INC. (US) 2017-07-25 US disclosed
US-20160033392-A1 STRUCTURE ASSESSMENT OF HETEROGENEOUS POLYPEPTIDE MIXTURE MOMENTA PHARMACEUTICALS, INC. 2016-02-04 US disclosed
US-9095547-B2 Structure assessment of heterogeneous polypeptide mixture MOMENTA PHARMACEUTICALS, INC. (US) 2015-08-04 US disclosed
CN-103110013-B Low-protein daily ration for growing pig under net energy system and application thereof LIAONING WELLHOPE AGRI TECH CO LTD 2014-07-02 CN disclosed
CN-203203992-U Blood collection device containing lysophospholipase inhibitor BECTON DICKINSON CO 2013-09-18 CN disclosed
CN-103110013-A Low-protein daily ration for growing pig under net energy system and application thereof LIAONING WELLHOPE AGRI TECH CO LTD 2013-05-22 CN disclosed
EP-0154234-A3 SUBSTITUTED TYROSIL ALANINE DIPEPTIDE AMIDES G.D. Searle & Co. (US) 1987-05-27 EP disclosed
EP-0154234-A3 SUBSTITUTED TYROSIL ALANINE DIPEPTIDE AMIDES G.D. Searle & Co. (US) 1987-05-27 EP disclosed
EP-0215297-A2 Substituted dipeptide amides G.D. Searle & Co. (US) 1987-03-25 EP disclosed
EP-0212550-A2 Substituted dipeptide amides G.D. Searle & Co. (US) 1987-03-04 EP disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed