SCHEMBL24905375

SCHEMBL24905375

c1ccc(-c2nc(-c3ccc(-c4ccc5c(c4)-c4ccccc4C54c5ccccc5-c5ccccc5-c5ccccc5-c5ccccc54)cc3)nc(-c3ccc4c(c3)oc3ccccc34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
KMT2A Q03164 6/20 0.37
MAPT P10636 6/20 0.37
MEN1 O00255 5/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HCRTR1 O43613 1/20 0.36
AHR P35869 2/20 0.35
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
ATM Q13315 3/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23437501 0.99 MMP12 (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL24039340 0.99 MAPT (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL24039308 0.99 MAPT (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL23437052 0.99 MMP12 (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL23437084 0.99 MMP12 (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL21867557 0.98 MMP12 (0.37) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL24039127 0.98 MAPT (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL24039307 0.98 MAPT (0.38) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL23437283 0.97 MMP12 (0.36) MMP12MMP13KMT2AMAPTMEN1
SCHEMBL23437543 0.97 MMP12 (0.36) MMP12MMP13KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed