SCHEMBL24905404

SCHEMBL24905404

c1ccc(N(c2ccc(-c3cccc4c3sc3ccccc34)cc2)c2ccc3c(c2)-c2ccccc2C32c3ccccc3C3(c4ccccc4-c4ccccc43)c3ccccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
PRKDC P78527 3/20 0.34
PARP14 Q460N5 1/20 0.33
APP P05067 1/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
F9 P00740 1/20 0.30
PIK3CD O00329 1/20 0.30
BRD4 O60885 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
KCNH2 Q12809 1/20 0.30
BRDT Q58F21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18457596 0.99 ALOX5 (0.46) ALOX5PRKDCPARP14APPTNKS
SCHEMBL24647924 0.96 ALOX5 (0.45) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL24904785 0.94 ALOX5 (0.44) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL24647618 0.94 ALOX5 (0.46) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL21558992 0.93 ALOX5 (0.41) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL21558993 0.93 ALOX5 (0.41) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL17804908 0.93 ALOX5 (0.43) ALOX5PRKDCPARP14
SCHEMBL19218541 0.92 ALOX5 (0.44) ALOX5PRKDCPARP14F9
SCHEMBL17855458 0.92 ALOX5 (0.44) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL17854476 0.92 ALOX5 (0.44) ALOX5PRKDCPARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed