Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490130 | 0.91 | GSK3B (0.48) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2487597 | 0.86 | GSK3B (0.49) | GSK3BCYP2D6 | |
| SCHEMBL3744211 | 0.76 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2486153 | 0.76 | GSK3B (0.50) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2490560 | 0.74 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2491257 | 0.73 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL2489761 | 0.72 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2489766 | 0.72 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2489764 | 0.72 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2487595 | 0.71 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057141-B1 | PYRIMIDONE COMPOUNDS AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2011-10-26 | — | — | EP | disclosed |