Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491914 | 0.89 | GSK3B (0.41) | GSK3BCYP2D6 | |
| SCHEMBL2490276 | 0.82 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL3737510 | 0.82 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL2490130 | 0.80 | GSK3B (0.48) | GSK3BCYP2D6 | |
| SCHEMBL3754542 | 0.79 | GSK3B (0.49) | GSK3BCYP2D6 | |
| SCHEMBL2489315 | 0.75 | GSK3B (0.49) | GSK3BCYP2D6 | |
| SCHEMBL2487402 | 0.75 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL2491003 | 0.75 | GSK3B (0.49) | GSK3BCYP2D6 | |
| SCHEMBL2491255 | 0.75 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL13046835 | 0.75 | GSK3B (0.49) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057141-B1 | PYRIMIDONE COMPOUNDS AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2011-10-26 | — | — | EP | disclosed |