Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 17/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141331 | 1.00 | SCN10A (0.41) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759003 | 0.92 | SCN10A (0.43) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757303 | 0.90 | SCN10A (0.43) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759025 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759024 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906249 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906385 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906227 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757797 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906235 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | GRUENENTHAL GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | SCN8A, SCN1A, SCN7A | SCN10A 8/4885ANO1 209/4885SLC2A1 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.