Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 17/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906317 | 1.00 | SCN10A (0.41) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759003 | 0.92 | SCN10A (0.43) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757303 | 0.90 | SCN10A (0.43) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759025 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759024 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906249 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906385 | 0.89 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906227 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757797 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906235 | 0.88 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | claimed |
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |