Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621312 | 0.81 | CYP11B1 (0.41) | CYP11B1CYP11B2LRRK2DRD4DRD3 | |
| SCHEMBL21637147 | 0.76 | DRD4 (0.37) | CYP11B1CYP11B2LRRK2DRD4DRD3 | |
| SCHEMBL13684190 | 0.69 | — | — | |
| SCHEMBL25189413 | 0.69 | — | — | |
| SCHEMBL24729136 | 0.69 | — | — | |
| SCHEMBL20074301 | 0.69 | — | — | |
| SCHEMBL20412605 | 0.68 | CYP11B1 (0.44) | CYP11B1CYP11B2LRRK2DRD4DRD3 | |
| SCHEMBL25259098 | 0.65 | CYP11B1 (0.44) | CYP11B1CYP11B2LRRK2DRD4DRD3 | |
| SCHEMBL18179471 | 0.65 | SSTR4 (0.45) | CYP11B1CYP11B2LRRK2DRD4DRD3 | |
| SCHEMBL14701579 | 0.65 | CYP11B1 (0.41) | CYP11B1CYP11B2LRRK2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004257-A1 | SULFONIMIDAMDE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2023-01-26 | — | — | WO | disclosed |