Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128622 | 0.84 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL2616090 | 0.83 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL2489001 | 0.83 | MAPT (0.56) | KDM4EALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL2491666 | 0.78 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL2131233 | 0.75 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL2615065 | 0.74 | SCD (0.54) | NPC1MEN1KMT2ARAB9APTGDR2 | |
| SCHEMBL2134596 | 0.74 | PTGDR2 (0.71) | PTGDR2 | |
| SCHEMBL2128855 | 0.74 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL2130877 | 0.74 | PTGDR2 (0.72) | PTGDR2 | |
| SCHEMBL2492504 | 0.74 | PTGDR2 (0.53) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |