Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491650 | 0.85 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL2133532 | 0.83 | PTGDR2 (0.79) | PTGDR2 | |
| SCHEMBL2130699 | 0.81 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL2493195 | 0.77 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL2487326 | 0.75 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL2489819 | 0.75 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL2489001 | 0.74 | MAPT (0.56) | PTGDR2 | |
| SCHEMBL2490835 | 0.74 | KDM4E (0.46) | PTGDR2 | |
| SCHEMBL2491666 | 0.73 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL2489027 | 0.73 | DEGS1 (0.50) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |