Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH4 | P08319 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22223 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL22876 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL37402 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL19711750 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL25273267 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL117989 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL25145215 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL577733 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL9801380 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 | |
| SCHEMBL23167 | 1.00 | EPHX1 (1.00) | EPHX1TSHRALDH1A1THRBS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560554-B2 | Lysosomal storage disease enzymes | ALEXION PHARMACEUTICALS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560554-B2 | Lysosomal storage disease enzymes | GAA, GBA1, MAN2B1 | EPHX1 2785/4885TSHR 1915/4885ALDH1A1 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.