SCHEMBL22223

SCHEMBL22223

CCCCCCCCCCCCCCNC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 1.00
TSHR P16473 2/20 0.56
ALDH1A1 P00352 1/20 0.56
THRB P10828 1/20 0.53
S1PR2 O95136 5/20 0.50
S1PR4 O95977 5/20 0.50
S1PR1 P21453 5/20 0.50
S1PR3 Q99500 5/20 0.50
S1PR5 Q9H228 1/20 0.50
ADH1B P00325 1/20 0.50
ADH1C P00326 1/20 0.50
ADH1A P07327 1/20 0.50
ADH4 P08319 1/20 0.50
ADH7 P40394 1/20 0.50
PPARA Q07869 2/20 0.44
LPAR3 Q9UBY5 2/20 0.43
LPAR2 Q9HBW0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22876 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL37402 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL19711750 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL25273267 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL117989 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL25145215 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL577733 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL24908635 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL9801380 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2
SCHEMBL23167 1.00 EPHX1 (1.00) EPHX1TSHRALDH1A1THRBS1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559428-B2 Metal oxide ceramic nanomaterials and methods of making and using same IVOCLAR VIVADENT AG (LI) 2026-02-24 US claimed
EP-4549620-A1 PROCESS FOR MAKING AMINES FROM NITRILE COMPOUNDS USING HYDROGEN HAVING LOW DEUTERIUM CONTENT PRODUCED WITH NON-FOSSIL ENERGY IN THE ABSENCE OF AMMONIA BASF SE (DE) 2025-05-07 EP claimed
CN-117447366-A Antistatic agent and preparation method and application thereof 广州梵泰新材料科技有限公司 2024-01-26 CN claimed
EP-3500539-B1 METAL OXIDE CERAMIC NANOMATERIALS AND METHODS OF MAKING AND USING SAME IVOCLAR VIVADENT AG (LI) 2023-12-13 EP claimed
CN-109843830-B Metal oxide ceramic nano material and preparation method and use method thereof 义获嘉伟瓦登特公司 2022-05-17 CN claimed
US-20220089501-A1 METAL OXIDE CERAMIC NANOMATERIALS AND METHODS OF MAKING AND USING SAME IVOCLAR VIVADENT AG (LI) 2022-03-24 US claimed
CN-108148394-B Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom 赢创运营有限公司 2021-12-28 CN claimed
CN-108166260-B Fiber sealing agent and preparation method thereof 广州市协运来实业有限公司 2020-07-14 CN claimed
EP-3500539-A1 METAL OXIDE CERAMIC NANOMATERIALS AND METHODS OF MAKING AND USING SAME Ivoclar Vivadent AG (LI) 2019-06-26 EP claimed
CN-109843830-A Metal oxide ceramic nano material and preparation method and use method thereof 义获嘉伟瓦登特公司 2019-06-04 CN claimed
EP-1319040-A1 POLYMER-ORGANOCLAY COMPOSITE COMPOSITIONS, METHOD FOR MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2003-06-18 EP claimed
US-6423768-B1 MIXTURES CONTAINING POLYAMIDES, POLYPHENYLENE ETHER AND IMPACT STRENGTH ADJUVANTS GENERAL ELECTRIC COMPANY 2002-07-23 US claimed
WO-2002022729-A1 POLYMER-ORGANOCLAY COMPOSITE COMPOSITIONS, METHOD FOR MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-03-21 WO claimed
US-5942486-A Dryer-activated laundry additive compositions with color care agents THE PROCTER & GAMBLE COMPANY (US) 1999-08-24 US claimed
US-5804547-A SUBSTRATE IN FORM OF SHEET CARRYING COLOR CARE COMPOSITION AND FABRIC SOFTENER THE PROCTER & GAMBLE COMPANY (US) 1998-09-08 US claimed
EP-0124200-B1 HEPARINIZATION OF PLASMA TREATED SUBSTRATES Becton Dickinson and Company (US) 1990-06-13 EP claimed
EP-0141628-B1 ANTIMICROBIAL LATEX COMPOSITION SHAPED ARTICLE PRODUCED THEREFROM, AND METHOD OF MANUFACTURING A SHAPED ARTICLE UNITIKA LTD. (JP) 1989-10-18 EP claimed
US-4468373-A Process for solvent extraction of vanadate and molybdate anions STANDARD OIL CO (INDIANA) (US) 1984-08-28 US claimed
US-4450114-A Process for production of sulfuric acid semiesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-22 US claimed
US-4351765-A Process for the production of compounds having in the molecule at least one β-sulfatoethyl-sulfone group and at least one sulfonic acid group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089501-A1 METAL OXIDE CERAMIC NANOMATERIALS AND METHODS OF MAKING AND USING SAME ZYX, IK, CTSZ EPHX1 4476/4885TSHR 4418/4885ALDH1A1 4438/4885
US-12559428-B2 Metal oxide ceramic nanomaterials and methods of making and using same CALR, CALD1, DGKZ EPHX1 4674/4885TSHR 2610/4885ALDH1A1 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.