SCHEMBL24909078

SCHEMBL24909078

Cc1ccc(OC(=O)C(Cc2cccc3c2oc2ccccc23)N2C(=O)c3cc(Oc4ccc(C)cc4C)c4c5c(Oc6ccc(C)cc6C)cc6c7c(cc(Oc8ccc(C)cc8C)c(c8c(Oc9ccc(C)cc9C)cc(c3c48)C2=O)c75)C(=O)N(C(Cc2cccc3c2oc2ccccc23)C(=O)Oc2ccc(C)cc2C)C6=O)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.36
KDM4E B2RXH2 2/20 0.33
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX5 P09917 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 3/20 0.33
DNMT1 P26358 2/20 0.33
DNMT3B Q9UBC3 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 4/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP3A4 P08684 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908944 0.95 KDM4E (0.36) HDAC8KDM4EHSD11B1ALDH1A1GLA
SCHEMBL24909302 0.86 HDAC8 (0.35) HDAC8KDM4EALDH1A1ALOX5GLA
SCHEMBL24909060 0.83 HPGD (0.34) HDAC8KDM4EALDH1A1GLAHPGD
SCHEMBL24704879 0.81
SCHEMBL24704947 0.79 HDAC8 (0.34) HDAC8KDM4EHSD11B1ALDH1A1ALOX5
SCHEMBL24705213 0.78 HSD11B1 (0.33) HDAC8KDM4EHSD11B1ALDH1A1CYP2C19
SCHEMBL24705437 0.76 HDAC8 (0.34) HDAC8KDM4EALDH1A1ALOX5HPGD
SCHEMBL24705423 0.75 EDNRB (0.33) HDAC8CYP2C19DNMT1DNMT3BPKM
SCHEMBL24908973 0.74 HSD11B1 (0.45) HSD11B1ALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL24908669 0.71 MCL1 (0.41) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed