SCHEMBL24909330

SCHEMBL24909330

Cc1ccc(Oc2cc3c4c(cc(Oc5ccc(C)cc5)c5c6c(Oc7ccc(C)cc7)cc7c8c(cc(Oc9ccc(C)cc9)c(c2c45)c86)C(=O)N(C(Cc2cc4ccccc4[nH]2)C(=O)N(C2CCCCC2)C2CCCCC2)C7=O)C(=O)N(C(Cc2cc4ccccc4[nH]2)C(=O)N(C2CCCCC2)C2CCCCC2)C3=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 2/20 0.37
TSHR P16473 4/20 0.36
KMT2A Q03164 3/20 0.34
POLB P06746 1/20 0.34
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.33
APAF1 O14727 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP2C19 P33261 3/20 0.33
DNMT1 P26358 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 1/20 0.33
DNMT3B Q9UBC3 1/20 0.33
PKM P14618 1/20 0.33
DRD3 P35462 1/20 0.32
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CXCR6 O00574 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909046 0.94 TSHR (0.35) CCKBRTSHRKMT2APOLBKDM4E
SCHEMBL24909639 0.80 PTH1R (0.32)
SCHEMBL24908761 0.80 TSHR (0.38) TSHRKMT2APOLBKDM4EALDH1A1
SCHEMBL24908734 0.78 TSHR (0.46) TSHRKMT2APOLBALDH1A1NPSR1
SCHEMBL24909183 0.78 GAA (0.39) TSHRKMT2APOLBKDM4EALDH1A1
SCHEMBL24908760 0.77 TSHR (0.39) TSHRKMT2APOLBALDH1A1CYP2C19
SCHEMBL24909182 0.77 TSHR (0.39) TSHRKMT2APOLBKDM4EALDH1A1
SCHEMBL24908736 0.77 TSHR (0.37) TSHRKMT2APOLBKDM4EHSD17B10
SCHEMBL24909635 0.76 KMT2A (0.35) TSHRKMT2APOLBKDM4EALDH1A1
SCHEMBL24705099 0.74 ALDH1A1 (0.60) TSHRKMT2APOLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed