SCHEMBL24909336

SCHEMBL24909336

N#Cc1cc(Br)c(O)c(-c2cc(F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.49
ALB P02768 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
RXRA P19793 2/20 0.38
RXRG P48443 2/20 0.38
RXRB P28702 1/20 0.35
KIF11 P52732 2/20 0.35
XDH P47989 1/20 0.34
VNN1 O95497 1/20 0.33
PGR P06401 1/20 0.32
TMPRSS4 Q9NRS4 1/20 0.32
EPAS1 Q99814 1/20 0.32
PTGDR2 Q9Y5Y4 2/20 0.31
TAS2R14 Q9NYV8 1/20 0.31
CYP1A2 P05177 1/20 0.31
METAP2 P50579 1/20 0.31
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909724 0.92 TTR (0.51) TTRALBMEN1KMT2ARXRA
SCHEMBL24909370 0.87 TTR (0.60) TTRALBMEN1KMT2APGR
SCHEMBL24909371 0.86 MEN1 (0.46) TTRALBMEN1KMT2ARXRA
SCHEMBL24909730 0.85 TTR (0.58) TTRALBMEN1KMT2APGR
SCHEMBL24909922 0.83 TTR (0.43) TTRALBMEN1KMT2ARXRA
SCHEMBL24910027 0.83 KIF11 (0.51) TTRALBMEN1KMT2ARXRA
SCHEMBL24909868 0.82 MEN1 (0.47) TTRALBMEN1KMT2ARXRA
SCHEMBL24909874 0.81 MEN1 (0.46) TTRALBMEN1KMT2ARXRA
SCHEMBL24910068 0.80 TTR (0.51) TTRALBMEN1KMT2APGR
SCHEMBL24909822 0.80 TTR (0.51) TTRALBMEN1KMT2APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.