SCHEMBL24909756

SCHEMBL24909756

COc1ccc(-c2cc(C#N)cc(Br)c2O)cc1F

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
ALB P02768 1/20 0.45
KMT2A Q03164 1/20 0.45
PTGS2 P35354 5/20 0.42
PTGS1 P23219 3/20 0.42
ERN1 O75460 1/20 0.42
KDM1A O60341 3/20 0.41
AR P10275 2/20 0.41
XDH P47989 1/20 0.41
GRM2 Q14416 1/20 0.40
PGR P06401 1/20 0.39
SLC22A12 Q96S37 1/20 0.38
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909689 0.90 MEN1 (0.45) MEN1TTRALBKMT2APTGS2
SCHEMBL24910051 0.85 MEN1 (0.45) MEN1TTRALBKMT2APTGS2
SCHEMBL24909751 0.84 AR (0.47) MEN1TTRALBKMT2AAR
SCHEMBL24909769 0.84 TTR (0.50) MEN1TTRALBKMT2AKDM1A
SCHEMBL24909772 0.84 TTR (0.53) MEN1TTRALBKMT2AAR
SCHEMBL24910002 0.83 MEN1 (0.46) MEN1TTRALBKMT2APTGS2
SCHEMBL24909748 0.82 AR (0.45) PTGS2PTGS1ERN1KDM1AAR
SCHEMBL24909899 0.82 MEN1 (0.45) MEN1TTRALBKMT2APTGS2
SCHEMBL24909858 0.80 MEN1 (0.51) MEN1TTRALBKMT2A
SCHEMBL24909765 0.78 TTR (0.56) MEN1TTRALBKMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.