SCHEMBL24909751

SCHEMBL24909751

COc1ccc(-c2cc(C#N)cc(Br)c2O)cc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.47
PGR P06401 5/20 0.47
PIM1 P11309 1/20 0.46
CTSS P25774 3/20 0.43
CTSK P43235 3/20 0.43
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42
ALB P02768 1/20 0.42
KMT2A Q03164 1/20 0.42
S1PR1 P21453 1/20 0.39
SLC22A12 Q96S37 2/20 0.37
XDH P47989 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909731 0.85 MEN1 (0.49) ARPGRMEN1TTRALB
SCHEMBL24909756 0.84 MEN1 (0.45) ARPGRMEN1TTRALB
SCHEMBL24909777 0.83 MEN1 (0.46) ARPGRCTSSCTSKMEN1
SCHEMBL24909340 0.83 AR (0.58) ARPGRMEN1TTRALB
SCHEMBL24910051 0.81 MEN1 (0.45) ARPGRMEN1TTRALB
SCHEMBL24909689 0.81 MEN1 (0.45) ARPGRMEN1TTRALB
SCHEMBL24909860 0.80 KIF11 (0.57) ARPGRMEN1TTRALB
SCHEMBL24910002 0.80 MEN1 (0.46) ARPGRMEN1TTRALB
SCHEMBL24909912 0.80 MEN1 (0.46) ARPGRMEN1TTRALB
SCHEMBL24909899 0.79 MEN1 (0.45) ARPGRMEN1TTRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 AR 3997/4885PGR 4667/4885PIM1 2419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.