Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865265 | 0.86 | RPS6KA3 (0.36) | RPS6KA3KCNK3KCNK9P2RY2P2RY1 | |
| SCHEMBL4734686 | 0.77 | CA1 (0.42) | RPS6KA3ALDH1A1SMN1; SMN2AAK1 | |
| SCHEMBL26375179 | 0.76 | PDE10A (0.40) | GPBAR1EGFRFGFR1KDRIDO1 | |
| SCHEMBL28857984 | 0.75 | RPS6KA3 (0.40) | RPS6KA3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21226299 | 0.75 | KCNK3 (0.33) | KCNK3KCNK9 | |
| SCHEMBL21725477 | 0.74 | CA12 (0.47) | RPS6KA3SLC6A2SLC6A4ALDH1A1LMNA | |
| SCHEMBL18068091 | 0.74 | KCNK3 (0.35) | KCNK3KCNK9APP | |
| SCHEMBL807278 | 0.73 | KCNK3 (0.52) | KCNK3KCNK9P2RY2P2RY1P2RY14 | |
| SCHEMBL26840510 | 0.73 | RPS6KA3 (0.37) | RPS6KA3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4076045 | 0.72 | PDE10A (0.40) | GPBAR1EGFRFGFR1KDRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-4122934-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-01-25 | — | — | EP | disclosed |