Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 14/20 | 0.36 |
| ▸ | JAK1 | P23458 | 14/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | TTK | P33981 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24910536 | 0.92 | PTK6 (0.42) | PTK6AURKBLCKTTK | |
| SCHEMBL22139118 | 0.92 | PTK6 (0.42) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL22142840 | 0.92 | PTK6 (0.42) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL25445338 | 0.90 | PTK6 (0.38) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL24910533 | 0.89 | PTK6 (0.42) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL24910580 | 0.88 | PTK6 (0.37) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL24910354 | 0.88 | PTK6 (0.41) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL24910620 | 0.88 | PTK6 (0.41) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL22124325 | 0.88 | PTK6 (0.46) | PTK6JAK2JAK1AURKBLCK | |
| SCHEMBL22123779 | 0.88 | PTK6 (0.52) | PTK6AURKBLCKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |