Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 16/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24912180 | 1.00 | APLNR (0.54) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL17542305 | 0.94 | APLNR (0.61) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL17542070 | 0.94 | APLNR (0.61) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL17542467 | 0.94 | APLNR (0.61) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL20630302 | 0.88 | APLNR (0.52) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL24912187 | 0.86 | APLNR (0.52) | APLNRTAS2R14 | |
| SCHEMBL20670351 | 0.82 | APLNR (0.46) | APLNRTAS2R14 | |
| SCHEMBL23670695 | 0.81 | APLNR (0.58) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL19284930 | 0.81 | APLNR (0.58) | APLNRTAS2R14L3MBTL1 | |
| SCHEMBL23670755 | 0.81 | APLNR (0.58) | APLNRTAS2R14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |