⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989092 | 0.80 | — | — | |
| SCHEMBL981790 | 0.78 | — | — | |
| Water SCHEMBL10814803 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2526119 | 0.76 | — | — | |
| SCHEMBL25124370 | 0.74 | BRD4 (0.39) | — | |
| SCHEMBL874304 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL909236 | 0.74 | — | — | |
| SCHEMBL7380304 | 0.74 | BRD4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL11837161 | 0.72 | ALDH1A1 (0.37) | — | |
| Bicarbonate SCHEMBL11614673 | 0.70 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957771-A | PHOSPHINIC ACID CHLORIDES, ALCOHOLS, HYDROLYSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | claimed |
| JP-1305081-A | — | — | None | — | — | JP | disclosed |
| EP-3932915-A1 | ACRYLOYL-CONTAINING NUCLEAR TRANSPORT REGULATOR AND USES THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2022-01-05 | — | — | EP | disclosed |
| US-20210053945-A1 | ACRYLOYL-CONTAINING NUCLEAR TRANSPORT REGULATORS AND USES THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2021-02-25 | — | — | US | disclosed |
| EP-3274352-B1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | Bayer Pharma AG (DE) | 2019-01-02 | — | — | EP | disclosed |
| US-9434740-B2 | Taxane compounds, compositions and methods | ODONATE THERAPEUTICS, LLC (US) | 2016-09-06 | — | — | US | disclosed |
| EP-2170059-B1 | CETP INHIBITORS DERIVED FROM BENZOXAZOLE ARYLAMIDES | MERCK SHARP & DOHME (US) | 2014-11-19 | — | — | EP | disclosed |
| US-8324198-B1 | Monocarbams | PFIZER INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120289455-A1 | Monocarbams | PFIZER INC. | 2012-11-15 | — | — | US | disclosed |
| US-8252782-B2 | Monocarbams | PFIZER INC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-0116432-A2 | Improvements in or relating to N-(substituted-methyl)-azetidin-2-ones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-08-22 | — | — | EP | disclosed |
| EP-0114128-A1 | 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation, their use as therapeutical agents and intermediates for their preparation | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | disclosed |
| US-4421686-A | 4-Norbornyl-sulfonyl azetidinone intermediates and process for preparing (S)-3-acylamino-4-substituted-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |
| EP-0060119-A1 | Azetidinone compounds and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4085100-A | Intermediate for dephthaloylation of azetidinone compounds | SMITHKLINE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4085100-A | Intermediate for dephthaloylation of azetidinone compounds | SMITHKLINE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-3957771-A | PHOSPHINIC ACID CHLORIDES, ALCOHOLS, HYDROLYSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |