Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30155850 | 1.00 | NSD2 (0.40) | NSD2BRD4PRMT5TMEM97SIGMAR1 | |
| SCHEMBL30155831 | 0.95 | SPR (0.38) | NSD2BRD4PRMT5TMEM97SIGMAR1 | |
| SCHEMBL30155795 | 0.95 | SPR (0.38) | NSD2BRD4PRMT5TMEM97SIGMAR1 | |
| SCHEMBL24913991 | 0.95 | SPR (0.38) | NSD2BRD4PRMT5TMEM97SIGMAR1 | |
| SCHEMBL24913993 | 0.95 | SPR (0.38) | NSD2BRD4PRMT5TMEM97SIGMAR1 | |
| SCHEMBL24913997 | 0.94 | TMEM97 (0.42) | NSD2TMEM97SIGMAR1PTGDR2ALDH1A1 | |
| SCHEMBL30155597 | 0.94 | TMEM97 (0.42) | NSD2TMEM97SIGMAR1PTGDR2ALDH1A1 | |
| SCHEMBL24913891 | 0.93 | TMEM97 (0.38) | PRMT5TMEM97SIGMAR1WDR77PTGDR2 | |
| SCHEMBL30155743 | 0.93 | TMEM97 (0.38) | PRMT5TMEM97SIGMAR1WDR77PTGDR2 | |
| SCHEMBL24913940 | 0.92 | TMEM97 (0.42) | TMEM97SIGMAR1PTGDR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |