Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 15/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130042 | 1.00 | CLPP (0.53) | CLPPCYP3A4L3MBTL1DRD2DRD4 | |
| SCHEMBL24914764 | 0.91 | CLPP (0.55) | CLPPENPP2MAPT | |
| SCHEMBL30130132 | 0.91 | CLPP (0.55) | CLPPENPP2MAPT | |
| SCHEMBL30130164 | 0.91 | CLPP (0.56) | CLPPENPP2MAPT | |
| SCHEMBL24914466 | 0.91 | CLPP (0.56) | CLPPENPP2MAPT | |
| SCHEMBL24914522 | 0.90 | CLPP (0.65) | CLPPCYP3A4DRD2DRD4DRD3 | |
| SCHEMBL30130034 | 0.90 | CLPP (0.65) | CLPPCYP3A4DRD2DRD4DRD3 | |
| SCHEMBL24914527 | 0.89 | CLPP (0.55) | CLPPMAPT | |
| SCHEMBL24914658 | 0.89 | CLPP (0.55) | CLPPMAPT | |
| SCHEMBL24914525 | 0.89 | CLPP (0.55) | CLPPDRD2DRD4DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284807-A1 | COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2023-01-19 | — | — | WO | disclosed |