SCHEMBL24914434

SCHEMBL24914434

N#Cc1cccc(CN2CCc3c(c(=O)n(Cc4ccc(Cl)cc4)c4nccn34)C2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CLPP Q16740 20/20 1.00
CYP3A4 P08684 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30130176 1.00 CLPP (1.00) CLPPCYP3A4
SCHEMBL30130102 0.94 CLPP (0.89) CLPPCYP3A4
SCHEMBL28984502 0.94 CLPP (0.89) CLPPCYP3A4
SCHEMBL24914421 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL24914420 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL30130081 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL24914564 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL30130028 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL30130035 0.92 CLPP (0.86) CLPPCYP3A4
SCHEMBL24915181 0.90 CLPP (0.82) CLPPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284807-A1 COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF 中国药科大学 2023-01-19 WO disclosed
CN-115611896-A Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof 中国药科大学 2023-01-17 CN disclosed