SCHEMBL24914714

SCHEMBL24914714

CNc1cc(Nc2ccccc2)cc(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
GAA P10253 1/20 0.50
THRB P10828 1/20 0.50
HPGD P15428 1/20 0.50
RHOA P61586 1/20 0.50
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
AR P10275 1/20 0.47
AKR1C3 P42330 5/20 0.46
AKR1C2 P52895 5/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17060018 0.87 MAPT (0.58) MAPTALDH1A1KDM4EHSD17B10GAA
SCHEMBL2884556 0.84 KDM4E (0.61) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL19730265 0.84 RHOA (0.61) GAARHOAMEN1KMT2ALMNA
SCHEMBL7080111 0.80 KDM4E (0.61) MAPTALDH1A1KDM4EHSD17B10GAA
SCHEMBL19730264 0.79 RHOA (0.62) ALDH1A1KDM4EGAARHOAMEN1
SCHEMBL3893904 0.79 MEN1 (0.50) MAPTALDH1A1KDM4EHSD17B10GAA
SCHEMBL9853268 0.77 NPSR1 (0.61) MAPTALDH1A1KDM4EHSD17B10GAA
3-Phenylamino Benzoic Acid SCHEMBL4345076 0.77 RHOA (0.77) MAPTALDH1A1KDM4EHSD17B10GAA
SCHEMBL399246 0.77 AKR1C3 (0.56) ALDH1A1KDM4ERHOAMEN1KMT2A
SCHEMBL29556844 0.77 AKR1C3 (0.56) ALDH1A1KDM4ERHOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119165-A1 NOVEL 3,5-DIAMINOBENZOIC ACID COMPOUND, AND PIN1 INHIBITOR AND THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES USING SAME Hiroshima University (JP) 2023-01-18 EP disclosed