SCHEMBL2884556

SCHEMBL2884556

CNc1cc(NC)cc(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
ALDH1A1 P00352 2/20 0.61
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
TPMT P51580 3/20 0.48
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
GPR35 Q9HC97 1/20 0.45
PKM P14618 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
CA3 P07451 1/20 0.42
MAPT P10636 1/20 0.42
SELL P14151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080111 0.95 KDM4E (0.61) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL15198821 0.87 ALDH1A1 (0.53) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL10932391 0.87 CA12 (0.60) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL12852899 0.87 TPMT (0.64) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL19005488 0.86 KDM4E (0.49) KDM4EALDH1A1MEN1KMT2ATPMT
Hydrochloric Acid SCHEMBL10935483 0.85 CA12 (0.58) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL12260647 0.85 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL14107722 0.85 TPMT (0.61) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL12878515 0.85 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2ATPMT
SCHEMBL24914714 0.84 MAPT (0.50) KDM4EALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654659-B1 Defined volume test device BOEHRINGER MANNHEIM CORP (US) 1997-02-12 EP claimed
EP-0345781-B1 Defined volume test device BOEHRINGER MANNHEIM CORP (US) 1995-08-30 EP claimed
EP-0654659-A1 Defined volume test device BOEHRINGER MANNHEIM CORPORATION (US) 1995-05-24 EP claimed
US-4994238-A Constant volume chemical analysis test device ROCHE DIABETES CARE, INC. 1991-02-19 US claimed
EP-0345781-A2 Defined volume test device BOEHRINGER MANNHEIM CORPORATION (US) 1989-12-13 EP claimed
US-11207645-B2 Composite semipermeable membrane and spiral wound separation membrane element NITTO DENKO CORPORATION (JP) 2021-12-28 US disclosed
US-20200061548-A1 COMPOSITE SEMIPERMEABLE MEMBRANE AND SPIRAL WOUND SEPARATION MEMBRANE ELEMENT NITTO DENKO CORPORATION (JP) 2020-02-27 US disclosed
US-9772568-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-26 US disclosed
US-20170174537-A1 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORPORATION (JP) 2017-06-22 US disclosed
US-20160291489-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-10-06 US disclosed
EP-2988596-A2 COMPOUNDS PROMOTING PLANT GROWTH Albert-Ludwigs-Universität Freiburg (DE) 2016-03-02 EP disclosed
US-20150344624-A1 CROSS-LINKING POLYMER, POLYMER RESIN COMPOSITION, AND POLYMER FILM KOLON INDUSTRIES, INC. (KR) 2015-12-03 US disclosed
EP-1789794-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES Applera Corporation, Applied Biosystems Group (US) 2007-05-30 EP disclosed
WO-2006031851-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES APPLERA CORPORATION (US) 2006-03-23 WO disclosed
US-20060063186-A1 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes APPLERA CORPORATION (US) 2006-03-23 US disclosed
EP-0654659-B1 Defined volume test device BOEHRINGER MANNHEIM CORP (US) 1997-02-12 EP disclosed
EP-0345781-B1 Defined volume test device BOEHRINGER MANNHEIM CORP (US) 1995-08-30 EP disclosed
EP-0654659-A1 Defined volume test device BOEHRINGER MANNHEIM CORPORATION (US) 1995-05-24 EP disclosed
US-4994238-A Constant volume chemical analysis test device ROCHE DIABETES CARE, INC. 1991-02-19 US disclosed
EP-0345781-A2 Defined volume test device BOEHRINGER MANNHEIM CORPORATION (US) 1989-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063186-A1 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes ABCG2, SLC46A1, QTRT1 KDM4E 1153/4885ALDH1A1 4046/4885MEN1 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.