Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 17/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130210 | 1.00 | CLPP (0.63) | CLPPMCHR1CYP3A4 | |
| SCHEMBL28984500 | 0.85 | CLPP (0.63) | CLPPCYP3A4 | |
| SCHEMBL30130297 | 0.80 | CLPP (0.48) | CLPPCYP3A4 | |
| SCHEMBL24914478 | 0.80 | CLPP (0.48) | CLPPCYP3A4 | |
| SCHEMBL30130239 | 0.79 | CLPP (0.49) | CLPP | |
| SCHEMBL24914779 | 0.79 | CLPP (0.49) | CLPP | |
| SCHEMBL24914432 | 0.79 | CLPP (0.66) | CLPPCYP3A4 | |
| SCHEMBL24915143 | 0.79 | CLPP (0.88) | CLPPCYP3A4 | |
| SCHEMBL30130083 | 0.79 | CLPP (0.88) | CLPPCYP3A4 | |
| SCHEMBL24914842 | 0.78 | CLPP (0.62) | CLPPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284807-A1 | COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2023-01-19 | — | — | WO | disclosed |
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |