Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 15/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130064 | 1.00 | CLPP (0.56) | CLPPMAPTDDB1CRBNTHRB | |
| SCHEMBL30130092 | 0.95 | CLPP (0.61) | CLPPMAPTDDB1CRBNENPP2 | |
| SCHEMBL24914512 | 0.95 | CLPP (0.61) | CLPPMAPTDDB1CRBNENPP2 | |
| SCHEMBL24914802 | 0.95 | CLPP (0.61) | CLPPMAPTDDB1CRBNENPP2 | |
| SCHEMBL30130060 | 0.94 | CLPP (0.54) | CLPPMAPTDDB1CRBNTHRB | |
| SCHEMBL24914819 | 0.94 | CLPP (0.54) | CLPPMAPTDDB1CRBNTHRB | |
| SCHEMBL30130056 | 0.94 | CLPP (0.54) | CLPPMAPTENPP2 | |
| SCHEMBL24914821 | 0.94 | CLPP (0.54) | CLPPMAPTDDB1CRBNTHRB | |
| SCHEMBL24914422 | 0.94 | CLPP (0.54) | CLPPMAPTENPP2 | |
| SCHEMBL24914469 | 0.93 | CLPP (0.54) | CLPPMAPTDDB1CRBNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284807-A1 | COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2023-01-19 | — | — | WO | disclosed |