SCHEMBL24914946

SCHEMBL24914946

C#CCNc1cccc(C(=O)Nc2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
PTGES O14684 16/20 0.38
RXFP1 Q9HBX9 2/20 0.37
CTSS P25774 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23059627 0.91 SMN1; SMN2 (0.39) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL28629194 0.90 SMN1; SMN2 (0.41) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL24914488 0.89 RXFP1 (0.39) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL28621337 0.87 SMN1; SMN2 (0.39) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL1766396 0.86 SMN1; SMN2 (0.43) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL29634361 0.86 SMN1; SMN2 (0.43) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL28620851 0.86 F2R (0.45) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL25085595 0.85 SMN1; SMN2 (0.38) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL31500621 0.85 SMN1; SMN2 (0.40) SMN1; SMN2PTGESRXFP1CTSS
SCHEMBL29161174 0.85 SMN1; SMN2 (0.44) SMN1; SMN2PTGESRXFP1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284645-A1 AMIDE COMPOUND AND USE THEREOF 沈阳化工大学 2023-01-19 WO disclosed