SCHEMBL2491537

SCHEMBL2491537

Brc1csc(/C=C/c2cc(Br)cs2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.40
MEN1 O00255 4/20 0.40
GAA P10253 4/20 0.40
KMT2A Q03164 4/20 0.40
RAB9A P51151 4/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
LMNA P02545 4/20 0.37
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
POLB P06746 1/20 0.36
STAT3 P40763 1/20 0.36
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491542 1.00 NPC1 (0.40) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL12877449 0.85
SCHEMBL5807863 0.81 CES2 (0.35) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL18345979 0.81 CES2 (0.35) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL4046986 0.79 AHR (0.48) MEN1KMT2AMAPTKDM4ETP53
SCHEMBL5807862 0.79 CES2 (0.34) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL4502372 0.79 MEN1 (0.30) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL4502377 0.79 MEN1 (0.30) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL14604972 0.79 MAPT (0.33) NPC1MEN1GAAKMT2ARAB9A
SCHEMBL5807860 0.79 CES2 (0.34) NPC1MEN1GAAKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2626375-B1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-11-22 EP disclosed
EP-2626375-B1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-11-22 EP disclosed
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 US disclosed
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 US disclosed
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 US disclosed
US-20160075808-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS USINVEST LLC 2016-03-17 US disclosed
US-20160075808-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS USINVEST LLC 2016-03-17 US disclosed
US-9221944-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2015-12-29 US disclosed
US-9221944-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2015-12-29 US disclosed
US-9221944-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2015-12-29 US disclosed
EP-2626375-A1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2013-08-14 EP disclosed
EP-2626375-A1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2013-08-14 EP disclosed
EP-2379617-B1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS BASF SE (DE) 2013-07-31 EP disclosed
EP-2379617-B1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS BASF SE (DE) 2013-07-31 EP disclosed
US-20120217482-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS POLYERA CORPORATION (US) 2012-08-30 US disclosed
US-20120217482-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS POLYERA CORPORATION (US) 2012-08-30 US disclosed
US-20120217482-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS POLYERA CORPORATION (US) 2012-08-30 US disclosed
EP-2379617-A2 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS BASF SE (DE) 2011-10-26 EP disclosed
WO-2010079064-A2 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS BASF SE (DE) 2010-07-15 WO disclosed
WO-2010079064-A2 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS BASF SE (DE) 2010-07-15 WO disclosed