Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016157 | 0.94 | MEN1 (0.52) | KMT2AMEN1CYP2A6CYP1A2TAAR1 | |
| SCHEMBL9552869 | 0.89 | KMT2A (0.56) | KMT2AMEN1TSHRHSD17B10HRH3 | |
| SCHEMBL8337927 | 0.82 | MEN1 (0.61) | KMT2AMEN1TAAR1SMN1; SMN2MAPT | |
| SCHEMBL8764230 | 0.82 | MEN1 (0.64) | KMT2AMEN1CYP2A6CYP1A2TSHR | |
| SCHEMBL23649359 | 0.81 | MEN1 (0.54) | KMT2AMEN1TAAR1TSHRKCNH2 | |
| SCHEMBL19263826 | 0.79 | CYP1A2 (0.59) | CYP2A6CYP1A2TAAR1HRH3KCNH2 | |
| SCHEMBL23512880 | 0.79 | KMT2A (0.47) | KMT2AMEN1TSHRHSD17B10HRH3 | |
| SCHEMBL9552639 | 0.79 | MAOB (0.53) | KMT2AMEN1CYP1A2TAAR1HSD17B10 | |
| SCHEMBL9552802 | 0.79 | TSHR (0.49) | KMT2AMEN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL26991588 | 0.79 | TSHR (0.58) | KMT2AMEN1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |