SCHEMBL2491635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17119915	0.82	TRPV1 (0.52)	ADORA2AADORA1ALDH1A1KDM4EHPGD
	SCHEMBL13869099	0.76	CYP2D6 (0.65)	ALDH1A1KDM4EHPGDHSD17B10CYP2D6
	SCHEMBL17119916	0.73	HRH3 (0.50)	CYP2D6CYP1A2OPRK1CYP2C19
	SCHEMBL2489517	0.73	ADORA2A (0.46)	ADORA2AADORA1ALDH1A1KDM4ECYP2D6
	SCHEMBL9052397	0.73	PTGS1 (0.38)	ADORA2AKDM4ERAB9AKMT2ANPC1
	SCHEMBL5309860	0.73	HTR2B (0.37)	ADORA2AADORA1ALDH1A1KDM4EHPGD
	SCHEMBL2494339	0.73	KDM4E (0.40)	ALDH1A1KDM4EHPGDHSD17B10RAB9A
	SCHEMBL29986186	0.73	PTGS1 (0.46)	ALDH1A1LMNATP53MAPTL3MBTL1
	SCHEMBL807235	0.72	KDM4E (0.68)	ALDH1A1KDM4ECYP2D6CYP1A2RAB9A
	SCHEMBL31010255	0.72	KDM4E (0.68)	ALDH1A1KDM4ECYP2D6CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.