Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494339 | 0.81 | KDM4E (0.40) | PTGS2HTR2BHTR5ATDO2PDE3B | |
| SCHEMBL5309860 | 0.81 | HTR2B (0.37) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL29986186 | 0.81 | PTGS1 (0.46) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL27650879 | 0.81 | PTGS1 (0.35) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL10584953 | 0.75 | PTGS1 (0.41) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL2491635 | 0.73 | ADORA2A (0.50) | ADORA2AKDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL996432 | 0.72 | CCNA2 (0.45) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL10381277 | 0.72 | HTR2B (0.41) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL321472 | 0.71 | CCNA2 (0.44) | PTGS1PTGS2HTR2BHTR5ATDO2 | |
| SCHEMBL10205841 | 0.71 | PTGS1 (0.46) | PTGS1PTGS2HTR2BHTR5ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004297-A9 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1996-05-02 | — | — | WO | disclosed |