Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 16/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24886267 | 0.89 | WDR5 (0.66) | WDR5PARP10PARP11PARP15PARP14 | |
| SCHEMBL24916294 | 0.83 | WDR5 (0.41) | WDR5PARP10PARP11PARP15PARP14 | |
| SCHEMBL24915771 | 0.83 | WDR5 (0.59) | WDR5PARP10PARP11 | |
| SCHEMBL25690834 | 0.83 | WDR5 (0.57) | WDR5KCNH2 | |
| SCHEMBL25690887 | 0.83 | WDR5 (0.58) | WDR5KCNH2 | |
| SCHEMBL29923383 | 0.80 | WDR5 (0.54) | WDR5KCNH2 | |
| SCHEMBL25187166 | 0.80 | WDR5 (0.54) | WDR5 | |
| SCHEMBL24886024 | 0.80 | WDR5 (0.68) | WDR5KCNH2 | |
| SCHEMBL24885645 | 0.80 | WDR5 (0.67) | WDR5 | |
| SCHEMBL24885997 | 0.79 | WDR5 (0.74) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-B1 | WDR5 INHIBITORS AND MODULATORS | UNIV VANDERBILT (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | WDR5 1/4885PARP10 482/4885PARP11 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.