Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 9/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 7/20 | 0.34 |
| ▸ | SYK | P43405 | 5/20 | 0.34 |
| ▸ | TTK | P33981 | 7/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916638 | 0.95 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| Hydrochloric Acid SCHEMBL30349748 | 0.94 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL22124722 | 0.94 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL22124854 | 0.93 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL22124566 | 0.93 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL30171789 | 0.93 | PDE10A (0.35) | PDE10AZAP70KARS1SYKTTK | |
| Formic Acid SCHEMBL22123789 | 0.91 | PDE10A (0.34) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL22125062 | 0.91 | ZAP70 (0.37) | PDE10AZAP70KARS1SYKTTK | |
| SCHEMBL24112394 | 0.90 | TTK (0.34) | ZAP70KARS1SYKTTKIDO1 | |
| SCHEMBL22123578 | 0.89 | SYK (0.36) | PDE10AZAP70KARS1SYKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017532-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017532-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | MRPL21, O60361, MYD88 | PDE10A 2096/4885ZAP70 716/4885KARS1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.