SCHEMBL24916698

SCHEMBL24916698

OC[C@@H]1CCO[C@H](CO)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.33
GBA1 P04062 6/20 0.33
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
SI P14410 1/20 0.31
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PYGL P06737 1/20 0.31
GBA2 Q9HCG7 1/20 0.31
GAA P10253 1/20 0.31
GLB1 P16278 1/20 0.31
LGALS1 P09382 2/20 0.30
LGALS9 O00182 1/20 0.30
LGALS8 O00214 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243000 0.83
SCHEMBL5594313 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL15145344 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL14339490 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL24246852 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL13969566 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL3748632 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL21479622 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL22640981 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA
SCHEMBL7772022 0.79 GBA2 (0.35) LGALS3GBA1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023288033-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed