SCHEMBL3748632

SCHEMBL3748632

OC[C@H]1OCC[C@@H](O)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GBA2 Q9HCG7 1/20 0.35
LGALS3 P17931 3/20 0.34
GBA1 P04062 3/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
LGALS1 P09382 2/20 0.31
LGALS9 O00182 1/20 0.31
LGALS8 O00214 1/20 0.31
TXNRD1 Q16881 1/20 0.31
TXNRD3 Q86VQ6 1/20 0.31
TXNRD2 Q9NNW7 1/20 0.31
PYGL P06737 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12083286 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL5594313 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL7772026 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL15145344 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL13969566 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL24246852 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL7772022 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL22640981 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL21479622 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR
SCHEMBL14339490 1.00 GBA2 (0.35) GBA2LGALS3GBA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103554194-B The manufacture method of sugar oxazoline derivative SEIKAGAKU KOGYO CO., LTD. (JP) 2016-03-09 CN claimed
US-20040033967-A1 Alkylated hexitol nucleoside analogues and oligomers thereof K.U.LEUVEN RESEARCH AND DEVELOPMENT (BE) 2004-02-19 US claimed
EP-0739333-B1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS DU PONT (US) 1998-10-14 EP claimed
WO-1997018222-A2 NOVEL OLIGOSACCHARIDE GLYCOSIDES HAVING MAMMALIAN IMMUNOSUPPRESSIVE AND TOLEROGENIC PROPERTIES GLYCOMED, INC. (US) 1997-05-22 WO claimed
EP-4326314-A2 AN FC GLYCAN REMODELING FOR SITE-SPECIFIC ANTIBODY CONJUGATION AND APPLICATIONS THEREOF University of Maryland, College Park (US) 2024-02-28 EP disclosed
US-20230276834-A1 COMPOSITION COMPRISING GLUCOSYLATED STEVIA AND HAVING IMPROVED SWEETNESS QUALITY CJ CHEILJEDANG CORPORATION (KR) 2023-09-07 US disclosed
WO-2023150695-A1 ALTERING NET CHARGE ON MANNOSYLATED DEXTRANS TO MAXIMIZE TARGET TISSUE UPTAKE AND OFF TARGET COMPETITIVE BLOCKING NAVIDEA BIOPHARMACEUTICALS, INC. (US) 2023-08-10 WO disclosed
EP-3119761-B1 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME AMYDIS DIAGNOSTICS INC (US) 2023-06-07 EP disclosed
US-11649222-B2 Compounds UNIVERSITETET I OSLO (NO) 2023-05-16 US disclosed
WO-2023011597-A1 LIGAND CONJUGATES FOR DELIVERY OF THERAPEUTICALLY ACTIVE AGENTS Hepagene Therapeutics (HK) Limited (CN) 2023-02-09 WO disclosed
US-11547681-B2 N-acylethanolamide derivatives and uses thereof ELIEM THERAPEUTICS, INC. (US) 2023-01-10 US disclosed
WO-2022226420-A2 AN FC GLYCAN REMODELING PLATFORM METHOD FOR SITE-SPECIFIC ANTIBODY CONJUGATION AND APPLICATIONS THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-27 WO disclosed
EP-0720616-A1 NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-07-10 EP disclosed
WO-1995021172-A1 PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST SMITHKLINE BEECHAM P.L.C. (GB) 1995-08-10 WO disclosed
EP-0655950-A1 CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY. SMITHKLINE BEECHAM PLC (GB) 1995-06-07 EP disclosed
WO-1995008557-A1 NOVEL OLIGOSACCHARIDE-CONTAINING 14-AMINOSTEROID COMPOUNDS AND NOVEL DIASTEREOSELECTIVE AMINOSTEROID PROCESS CHEMISTRY THE PROCTER & GAMBLE COMPANY (US) 1995-03-30 WO disclosed
WO-1995008558-A1 NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1995-03-30 WO disclosed
WO-1994003271-A1 CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY SMITHKLINE BEECHAM PLC (GB) 1994-02-17 WO disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed
EP-0089812-A1 N-substituted pseudo-aminosugars, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033967-A1 Alkylated hexitol nucleoside analogues and oligomers thereof DERA, HEXA, HEXB GBA2 735/4885LGALS3 558/4885GBA1 475/4885
US-11649222-B2 Compounds SLC30A6, SLC39A11, SLC39A3 GBA2 336/4885LGALS3 2852/4885GBA1 468/4885
US-11547681-B2 N-acylethanolamide derivatives and uses thereof FAAH, FAAH2, NAAA GBA2 100/4885LGALS3 2543/4885GBA1 141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.