SCHEMBL24916705

SCHEMBL24916705

C=C(C)c1c(F)c(F)c(F)c(F)c1OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18481135 0.89 MEN1 (0.34) CYP2C9MEN1KMT2ACYP1A2
SCHEMBL646711 0.77 TYMP (0.31)
SCHEMBL18480975 0.77 RECQL (0.33)
SCHEMBL24916693 0.77
SCHEMBL29710578 0.73 KMT2A (0.49) CYP2C9MEN1KMT2ACYP1A2
SCHEMBL9378544 0.73 KMT2A (0.49) CYP2C9MEN1KMT2ACYP1A2
SCHEMBL22969307 0.72
SCHEMBL20047250 0.71 RECQL (0.30)
SCHEMBL11440464 0.71 KMT2A (0.41) CYP2C9MEN1KMT2ACYP1A2
SCHEMBL182607 0.71 HSD17B10 (0.40) CYP2C9MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023288033-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed