SCHEMBL182607

SCHEMBL182607

COc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2C9 P11712 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 1/20 0.30
ACHE P22303 1/20 0.30
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3763099 0.96 HSD17B10 (0.41) HSD17B10CA1CA2CA9KDM4E
SCHEMBL4951694 0.92 HSD17B10 (0.35) HSD17B10CA1CA2CA9KDM4E
SCHEMBL12965347 0.90 HSD17B10 (0.45) HSD17B10CA1CA2CA9CYP2C9
SCHEMBL396821 0.87 HSD17B10 (0.35) HSD17B10
SCHEMBL1711725 0.86 HSD17B10 (0.47) HSD17B10KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL12089524 0.85 HSD17B10 (0.34) HSD17B10CYP2C9MEN1KMT2ACYP1A2
SCHEMBL107339 0.83 HSD17B10 (0.36) HSD17B10SMN1; SMN2CYP2C9MEN1KMT2A
SCHEMBL10019857 0.83 HSD17B10 (0.36) HSD17B10CYP2C9MEN1KMT2ACYP1A2
SCHEMBL7784272 0.83 HSD17B10 (0.32) HSD17B10CA1CA2CA9
SCHEMBL10019862 0.83 HSD17B10 (0.33) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260112696-A1 ELECTROLYTE SOLUTION OF LITHIUM-ION BATTERY AND LITHIUM SECONDARY BATTERY ZHANGJIAGANG GUOTAI-HUARONG NEW CHEMICAL MATERIALS CO., LTD. (CN) 2026-04-23 US claimed
EP-4607644-A1 ELECTROLYTE SOLUTION OF LITHIUM-ION BATTERY AND LITHIUM SECONDARY BATTERY Zhangjiagang Guotai-Huarong New Chemical Materials Co., Ltd (CN) 2025-08-27 EP claimed
CN-117525579-B Lithium ion battery electrolyte and lithium ion battery 张家港市国泰华荣化工新材料有限公司 2025-05-02 CN claimed
CN-119340480-A Nonaqueous electrolyte and lithium secondary battery 张家港市国泰华荣化工新材料有限公司 2025-01-21 CN claimed
CN-119340479-A Nonaqueous electrolyte and lithium secondary battery 张家港市国泰华荣化工新材料有限公司 2025-01-21 CN claimed
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
WO-2024083011-A1 ELECTROLYTE SOLUTION OF LITHIUM-ION BATTERY AND LITHIUM SECONDARY BATTERY 张家港市国泰华荣化工新材料有限公司 2024-04-25 WO claimed
CN-117917792-A Lithium ion battery electrolyte and lithium secondary battery 张家港市国泰华荣化工新材料有限公司 2024-04-23 CN claimed
CN-117497858-A Electrolyte and lithium ion battery 蜂巢能源科技股份有限公司 2024-02-02 CN claimed
CN-114171792-B Secondary battery electrolyte and secondary battery 张家港市国泰华荣化工新材料有限公司 2023-12-05 CN claimed
US-20030083331-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2003-05-01 US claimed
US-20030032644-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-02-13 US claimed
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US claimed
US-6274529-B1 COORDINATION CATALYST CONTAINS METALLOCENE OF HAFNIUM, TITANIUM, OR ZIRCONIUM, AND HETEROCOMPOUND CONTAINING OXYGEN, NITROGEN, SULFUR, AND/OR PHOSPHORUS ENICHEM S.P.A. (IT) 2001-08-14 US claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
WO-2001029920-A1 SHUTDOWN AND REDOX SHUTTLE ADDITIVES FOR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-04-26 WO claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
EP-0771822-A1 Catalytic system for the (co)polymerization of alpha-olefins ENICHEM S.p.A. (IT) 1997-05-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, LCAT, MTTP HSD17B10 419/4885CA1 4825/4885CA2 4562/4885
US-20030083331-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity CETP, MTTP, LCAT HSD17B10 374/4885CA1 4821/4885CA2 4443/4885
US-20030032644-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity CETP, MTTP, PCTP HSD17B10 257/4885CA1 4538/4885CA2 3853/4885
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, DBI, PLTP HSD17B10 553/4885CA1 4774/4885CA2 4517/4885
US-20260112696-A1 ELECTROLYTE SOLUTION OF LITHIUM-ION BATTERY AND LITHIUM SECONDARY BATTERY KCNN2, KCNN1, HCN2 HSD17B10 1171/4885CA1 136/4885CA2 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.