SCHEMBL2491698

SCHEMBL2491698

C=C(C)C(=O)OC[Si](CCCC)(OCC)OCC

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.33
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16536853 0.90 THRB (0.44) TSHRTHRBALDH1A1
SCHEMBL19125098 0.86 TSHR (0.60) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL27933912 0.86 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL27616681 0.84 TSHR (0.63) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL338995 0.83 THRB (0.47) TSHRTHRBALDH1A1
SCHEMBL7597930 0.80 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1269949 0.79 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL16537891 0.78 TSHR (0.58) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL29249573 0.77 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL339522 0.77 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970659-A1 POLYMERS AND POLYMER BLENDS WITH ENHANCED GLOSS LEVEL Covestro LLC (US) 2016-01-20 EP disclosed
WO-2014164623-A1 POLYMERS AND POLYMER BLENDS WITH ENHANCED GLOSS LEVEL BAYER MATERIALSCIENCE LLC (US) 2014-10-09 WO disclosed
EP-2558536-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING Styron Europe GmbH (CH) 2013-02-20 EP disclosed
EP-2545122-A1 IMPACT MODIFIED IGNITION RESISTANT CARBONATE POLYMER COMPOSITION Styron Europe GmbH (CH) 2013-01-16 EP disclosed
WO-2011130754-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON EUROPE GMBH (CH) 2011-10-20 WO disclosed
WO-2011128119-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON EUROPE GMBH (CH) 2011-10-20 WO disclosed
WO-2011110365-A1 IMPACT MODIFIED IGNITION RESISTANT CARBONATE POLYMER COMPOSITION STYRON EUROPE GMBH (CH) 2011-09-15 WO disclosed
US-20040106731-A1 Poly(ester) carbonate molding compositions COVESTRO DEUTSCHLAND AG (DE) 2004-06-03 US disclosed