Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.75 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | TTPA | P49638 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.62 |
| ▸ | AKT1 | P31749 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714113 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL18687258 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL13017369 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL15102111 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL23076488 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL15478529 | 1.00 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL16379033 | 0.95 | MEN1 (0.69) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL3514286 | 0.92 | MEN1 (0.77) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL16156486 | 0.91 | MEN1 (0.75) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL17586141 | 0.91 | MEN1 (0.62) | MEN1KMT2APDE4APDE3AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014151-A1 | COMBINATION ANTIVIRAL THERAPY FOR MEASLES | CORNELL UNIVERSITY | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230014151-A1 | COMBINATION ANTIVIRAL THERAPY FOR MEASLES | HM13, LRPPRC, TFRC | MEN1 382/4885KMT2A 3491/4885PDE4A 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.